DASOFEN2018-12-10T01:14:34+00:00
Dasofen

25×10 Blister

Serratiopeptidase           10 mg

Diclofenac Potassium      50 mg

Serratiopeptidase  is a proteolytic enzyme obtained from the silkworm. It is used to reduce pain and swelling associated with conditions like back pain, arthritis, tension headaches and migraine headaches.

Diclofenac  is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity.

  • Bones and joints pain
  • Inflammation
  • Edema
  • Dental pain
  • Migraine
  • Menstrual pain
  • Painful conditions (Osteoarthritis, Rheumatoid Arthritis, Osteoporosis, Fibromyalgia)
  • Muscles pain

Please consult your physician or pharmacist or refer to product package.

Diclofenac exerts potent anti-inflammatory, anti-pyretic and analgesic activity by inhibition of cyclooxygenase pathway (COX) and thus inhibits biosynthesis of prostaglandin and other pro-inflammatory mediators of pain pathway.

Serratiopeptidase, a bacterial peptide-cleaving enzyme obtained from Serratia marcescens. Serratiopeptidase is also a potent anti-inflammatory agent that exerts fibrinolytic and anti-edematic property. The therapeutic enzyme reduce inflammation and swelling in the affected area.

Absorption

After oral/IM or rectal administration, Diclofenac sodium + Serratiopeptidase is rapidly absorbed in the GIT. However, the absorption rate is very slow in enteric-coated formulations.

Distribution

The drug can enter breast milk and synovial fluid after distribution. The plasma protein binding capability of this product is about 99%.

Metabolism

Metabolized in the liver and converted into active metabolites.

Elimination

The drug is extensively excreted in urine as glucuronide and sulfate conjugates. The rest of the elimination is via the bile. The terminal half-life is about 1-2 hours.

  • Indigestion, gas, stomach pain, nausea, vomiting
  • Diarrhea, constipation;
  • Headache, dizziness, drowsiness;
  • Itching, increased sweating;
  • Increased blood pressure; or.
  • Swelling or pain in your arms or legs.
  • Asthma
  • Heart disease
  • liver disease
  • During pregnancy
  • Stomach/Intestinal/Esophagus problem
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